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Effects of Aging and Anti-Aging Caloric Restrictions on Carbonyl and Heat Shock Protein Levels and Expression

✍ Scribed by C. Colotti; G. Cavallini; R. L. Vitale; A. Donati; M. Maltinti; S. Del Ry; E. Bergamini; D. Giannessi

Publisher: Springer
Year: 2005
Tongue: English
Weight: 269 KB
Volume: 6
Category: Article
ISSN: 1389-5729
DOI: 10.1007/s10522-005-4906-z

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## Abstract In __C. elegans,__ insulin‐like hormone signal pathway plays a significant role in longevity. In particular, __daf‐16__ gene product is indispensable factor for this lifespan‐extension. This signal pathway is critical for dauer formation, which is a similar state to hibernation in mamma