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Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1,3-dimethyluric acid formation

โœ Scribed by Su Yeon Yu; Hye Chin Chung; Eun Jung Kim; So Hee Kim; Inchull Lee; Sang Geon Kim; Myung Gull Lee

Book ID
111769148
Publisher
Pharmaceutical Press
Year
2002
Tongue
English
Weight
194 KB
Volume
54
Category
Article
ISSN
2042-7158

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โœ Choong Y. Ahn; Eun J. Kim; Inchul Lee; Jong W. Kwon; Won B. Kim; Sang G. Kim; My ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 119 KB ๐Ÿ‘ 2 views

The effects of glucose on CYP2E1 expression in rats with acute renal failure induced by uranyl nitrate (U-ARF) have been reported. CYP2E1 was significantly induced (2.3-fold) in rats with U-ARF compared with that in control rats. In contrast, CYP2E1 expression was significantly decreased in rats wit