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Effects of a thromboxane synthetase inhibitor on platelet function; possible risks of use in pregnancy

โœ Scribed by M.H.F. Sullivan; Y. Ahmed; M.G. Elder


Book ID
119051487
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
326 KB
Volume
46
Category
Article
ISSN
0090-6980

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The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini