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Effects of a combined treatment with tamoxifen and estrogen receptor β agonists on human breast cancer cell lines

✍ Scribed by Claus Lattrich, Susanne Schüler, Julia Häring…

Book ID: 120891158
Publisher: Springer
Year: 2013
Tongue: English
Weight: 401 KB
Volume: 289
Category: Article
ISSN: 0003-9128
DOI: 10.1007/s00404-013-2977-7

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## Abstract Although tamoxifen (TAM) is used for the front‐line treatment and prevention of estrogen receptor‐positive (ER+) breast tumors, nearly 40% of estrogen‐dependent breast tumors do not respond to TAM treatment. Moreover, the positive response is usually of short duration, and most tumors e