Effects of 4-nitroquinoline 1-oxide on the DNA-protein complex
โ Scribed by Ohara, Susumu
- Book ID
- 123535110
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 252 KB
- Volume
- 84
- Category
- Article
- ISSN
- 1096-4959
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## Abstract The carcinogen 4โnitroquinolineโ1โoxide (4NQO) is known to induce unscheduled DNA synthesis when administered to a number of mammalian cells. This effect was demonstrated in human lymphocytes. The degree of unscheduled DNA synthesis was found to be correlated with time and with 4NQO con
## Abstract The shortโterm effects of the carcinogen 4โNitroquinoline 1โoxide (NQO) on the number of plaqueโforming spleen cells (PFC) after immunization with sheep erythrocytes have been tested in (C57BL ร IF) mice. The number of PFC was reduced in the NQOโtreated mice and this reduction was great