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Binding of 14C-labeled 4-nitroquinoline 1-oxide to DNA in vivo

✍ Scribed by S. Ikegami; N. Nemoto; S. Sato; T. Sugimura


Book ID
113135144
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
771 KB
Volume
1
Category
Article
ISSN
0009-2797

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## Abstract The carcinogen 4‐nitroquinoline‐1‐oxide (4NQO) is known to induce unscheduled DNA synthesis when administered to a number of mammalian cells. This effect was demonstrated in human lymphocytes. The degree of unscheduled DNA synthesis was found to be correlated with time and with 4NQO con