Effects of 4-MA, a potent inhibitor of 5α-reductase, on 3β-hydroxysteroid dehydrogenase/Δ5−Δ4-isomerase activity in guinea pig adrenals
✍ Scribed by Sylvie Perron; Alain Bélanger
- Book ID
- 116065882
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 650 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0039-128X
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The activity of 3 beta-hydroxysteroid dehydrogenase delta 4-5 isomerase (3 beta-HSD) was assayed in various tissues microdissected from the freeze-dried human skin of 13 subjects. The sebaceous gland possessed the highest activity of 3 beta-HSD in the skin, while the apocrine sweat gland showed only
## Abstract Little information is available for neurosteroidogenesis in the central nervous system (CNS) of lower vertebrates. Therefore, in the present study, we examined the enzymatic activity and localization of 3β‐hydroxysteroid dehydrogenase/Δ^5^‐Δ^4^‐isomerase (3βHSD), a key steroidogenic enz