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Effector CD8+CD45RO−CD27−T cells have signalling defects in patients with squamous cell carcinoma of the head and neck

✍ Scribed by Kuss, I; Donnenberg, A D; Gooding, W; Whiteside, T L

Book ID
121218680
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
226 KB
Volume
88
Category
Article
ISSN
0007-0920

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## Abstract ## Background Homeostasis of circulating T cells is regulated in complex ways that have not yet been well defined. The balance between type 1 and type 2 T‐cell subsets in cancer patients is thought to modulate antitumor immunity. Meanwhile, CD4+CD25+ regulatory T cells (Treg), which ar