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CD45RA-Foxp3highbut not CD45RA+Foxp3lowsuppressive T regulatory cells increased in the peripheral circulation of patients with head and neck squamous cell carcinoma and correlated with tumor progression

✍ Scribed by Sun, Wei; Li, Wei-Jin; Wu, Chang-You; Zhong, Hua; Wen, Wei-Ping


Book ID
125403627
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
817 KB
Volume
33
Category
Article
ISSN
1756-9966

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## Abstract ## Background Homeostasis of circulating T cells is regulated in complex ways that have not yet been well defined. The balance between type 1 and type 2 T‐cell subsets in cancer patients is thought to modulate antitumor immunity. Meanwhile, CD4+CD25+ regulatory T cells (Treg), which ar