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Effectiveness of tocotrienol-rich fraction combined with tamoxifen in the management of women with early breast cancer: a pilot clinical trial

✍ Scribed by Kalanithi Nesaretnam; Kanga Rani Selvaduray; Ghazali Abdul Razak; Sheela Devi Veerasenan; Patricia A Gomez


Book ID
119915576
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
656 KB
Volume
12
Category
Article
ISSN
1465-5411

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## BACKGROUND. Tamoxifen (TAM) is generally considered the hormonal agent of choice for postmenopausal women with hormone receptor positive breast carcinoma. The somatostatin analogues, including octreotide, have demonstrated inhibition of breast carcinoma cell lines and multiple endocrinologic act

Anastrozole alone or in combination with
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## Abstract ## BACKGROUND The first analysis of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial (median follow‐up, 33 months) demonstrated that in adjuvant endocrine therapy for postmenopausal patients with early‐stage breast cancer, anastrozole was superior to tamoxifen in terms of d