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Effectiveness of cancer vaccine therapy using cells transduced with the interleukin-12 gene combined with systemic interleukin-18 administration

✍ Scribed by Hara, Isao; Nagai, Hiroshi; Miyake, Hideaki; Yamanaka, Kazuki; Hara, Shoji; Micallef, Mark J; Kurimoto, Masashi; Gohji, Kazuo; Arakawa, Soichi; Ichihashi, Masamitsu


Book ID
110017642
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
182 KB
Volume
7
Category
Article
ISSN
0929-1903

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Controlled systemic release of interleuk
✍ Gregor Tevz; Simona Kranjc; Maja Cemazar; Urska Kamensek; Andrej Coer; Mojca Krz πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 490 KB

## Abstract ## Background The present study aimed to evaluate the antitumor effectiveness of systemic __interleukin (IL)‐12__ gene therapy in murine sarcoma models, and to evaluate its interaction with the irradiation of tumors and metastases. To avoid toxic side‐effects of __IL‐12__ gene therapy,