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Antitumor effects of the combination therapy with TNF-α gene–modified tumor cells and interleukin 12 in a melanoma model in mice

✍ Scribed by Lasek, Witold; Mackiewicz, Andrzej; Czajka, Anna; Świtaj, Tomasz; Gołąb, Jakub; Wiznerowicz, Maciej; Korczak-Kowalska, Grażyna; Bakowiec-Iskra, Ewa Z; Gryska, Katarzyna; Iżycki, Dariusz

Book ID
110017773
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
222 KB
Volume
7
Category
Article
ISSN
0929-1903

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## Abstract Lovastatin, the drug used for the treatment of hypercholesterolemia, has previously been reported to exert antitumor activity in experimental murine models. Butyrate and butyric acid derivatives are well known to induce differentiation and apoptosis of tumour cells and also have recentl