Combination Therapy of Colon Carcinoma 26 in Mice with Recombinant Human Interleukin-2 and Interferon-α A/D: Occurrence of Large Granular Cells in the Tumor
✍ Scribed by Sakura, Yasufumi ;Ootsu, Koichiro ;Shino, Akio
- Book ID
- 108578876
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1989
- Tongue
- English
- Weight
- 996 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0910-5050
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Five partial responses were seen in 23 patients with metastatic renal-cell carcinoma (MRCC) receiving interferon-a 2a (IFN) + prednisone (P). Four of 24 subsequent patients responded to IFN + P (combined response rate 19%). The median response duration was 8 months (3 to 30 months). The one-year sur
## Background: The main objective of this trial was to evaluate the combination of subcutaneous (sc) interleukin-2 (il-2) with interferon alpha-2a (ifn-alpha) in the treatment of patients with metastatic renal cell carcinoma (mrcc) compared with a previous trial that used continuous-infusion il-2 a