This study was conducted to comprehensively evaluate the performance of various allometric scaling methods for the prediction of human clearance. Allometric scaling was used to predict clearance for 103 compounds, for which clearance data in the rat, dog, monkey, and humans were available. Allometry
โฆ LIBER โฆ
Effectiveness of aprotinin in blocking a hypotensive factor of pancreatic origin from the pig, dog and monkey
โ Scribed by L.William Traverso
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 545 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0300-9572
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In Table 3, the MAE value for three-species allometric scaling using the rule of exponents should be 6.44, not 11.03 as originally cited. This error resulted from an incorrect predicted value for one of the 103 compounds in the dataset (nicotine; incorrect error of 479.6 mL/min/kg rather than the co