This study was conducted to comprehensively evaluate the performance of various allometric scaling methods for the prediction of human clearance. Allometric scaling was used to predict clearance for 103 compounds, for which clearance data in the rat, dog, monkey, and humans were available. Allometry
โฆ LIBER โฆ
Erratum: A comprehensive analysis of the role of correction factors in the allometric predictivity of clearance from rat, dog, and monkey to humans
โ Scribed by Rakesh Nagilla; Keith W. Ward
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 40 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0022-3549
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โฆ Synopsis
In Table 3, the MAE value for three-species allometric scaling using the rule of exponents should be 6.44, not 11.03 as originally cited. This error resulted from an incorrect predicted value for one of the 103 compounds in the dataset (nicotine; incorrect error of 479.6 mL/min/kg rather than the correct 9.28 mL/min/kg), skewing the original MAE value. The corrected Table follows.
๐ SIMILAR VOLUMES
A comprehensive analysis of the role of
โ
Rakesh Nagilla; Keith W. Ward
๐
Article
๐
2004
๐
John Wiley and Sons
๐
English
โ 229 KB