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Erratum: A comprehensive analysis of the role of correction factors in the allometric predictivity of clearance from rat, dog, and monkey to humans

โœ Scribed by Rakesh Nagilla; Keith W. Ward


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
40 KB
Volume
94
Category
Article
ISSN
0022-3549

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โœฆ Synopsis


In Table 3, the MAE value for three-species allometric scaling using the rule of exponents should be 6.44, not 11.03 as originally cited. This error resulted from an incorrect predicted value for one of the 103 compounds in the dataset (nicotine; incorrect error of 479.6 mL/min/kg rather than the correct 9.28 mL/min/kg), skewing the original MAE value. The corrected Table follows.


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A comprehensive analysis of the role of
โœ Rakesh Nagilla; Keith W. Ward ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 229 KB

This study was conducted to comprehensively evaluate the performance of various allometric scaling methods for the prediction of human clearance. Allometric scaling was used to predict clearance for 103 compounds, for which clearance data in the rat, dog, monkey, and humans were available. Allometry