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Effectivein vivoinduction of lymphokine-activated killer (LAK) cells by pretreatment with a streptococcal preparation, OK-432

โœ Scribed by Katsuhiro Shimoda; Takao Saito; Michio Kobayashi; Kikuo Nomot


Publisher
Springer
Year
1992
Tongue
English
Weight
634 KB
Volume
5
Category
Article
ISSN
0921-299X

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The natural-killer(NK)-cell-mediated cytotoxicity to syngeneic tumor cells can be augmented by in vivo priming and subsequent in vitro challenge with the streptococcal preparation OK432. Supernatants of cocultures of spleen cells with OK432 contained interleukin-2 (IL-2) and interferon (IFN), mainly