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Effective inhibition of mRNA accumulation and protein expression of H5N1 avian influenza virus NS1 gene in vitro by small interfering RNAs

✍ Scribed by Jiao, Hanwei; Du, Li; Hao, Yongchang; Cheng, Ying; Luo, Jing; Kuang, Wenhua; Zhang, Donglin; Lei, Ming; Jia, Xiaoxiao; Zhang, Xiaoru; Qi, Chao; He, Hongxuan; Wang, Fengyang

Book ID
120388665
Publisher
Springer Netherlands
Year
2012
Tongue
English
Weight
408 KB
Volume
58
Category
Article
ISSN
0015-5632

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## Abstract ## Background Highly pathogenic avian influenza virus H5N1 can cause acute respiratory infections with an uncontrolled virus‐induced cytokine storm in both poultry and humans. In view of the high mortality of H5N1 influenza virus infection, the development of novel broad‐spectrum proph