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Inhibition of highly pathogenic avian H5N1 influenza virus replication by RNA oligonucleotides targeting NS1 gene

✍ Scribed by Yanhua Wu; Guozhong Zhang; Yi Li; Yi Jin; Rod Dale; Lun-Quan Sun; Ming Wang

Book ID
116295937
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
379 KB
Volume
365
Category
Article
ISSN
0006-291X

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## Abstract ## Background Highly pathogenic avian influenza virus H5N1 can cause acute respiratory infections with an uncontrolled virus‐induced cytokine storm in both poultry and humans. In view of the high mortality of H5N1 influenza virus infection, the development of novel broad‐spectrum proph