𝔖 Bobbio Scriptorium
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Effective Absorption Modeling in Relative Bioavailability Study Risk Assessment

✍ Scribed by Rose, John P.


Book ID
115533004
Publisher
American Association of Pharmaceutical Scientists
Year
2012
Tongue
English
Weight
391 KB
Volume
14
Category
Article
ISSN
1550-7416

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A two-compartment disposition model of ascorbic acid (AA) pharmacokinetics with saturable and time-constrained intestinal absorption was developed. The model was fitted to pharmacokinetic data obtained after oral administration to nine healthy volunteers of two effervescent dosage forms differing in