In vitro ADP-ribosylation of chromosomal proteins and its modulation by spermine, 3-aminobenzamide (3-AB) and benzamide were studied by incubating the nuclei of cerebral hemisphere of 3-, 14-and 30-day old rats with 32p-NAD Β§ Histones get ADP-ribosylated more than the non-histone chromosomal (NHC) p
Effect ofin vitro(ADP)ribosylation on transcription of the chromatin of the brain of developing rats
β Scribed by B. R. Das; M. S. Kanungo
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 274 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0301-4851
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## Abstract Poly ADPβribosylation is a postβtranslational modification of chromatin proteins catalyzed by the enzyme polyβADPR transferase (polyβADPRT) and affects the structure as well as the functional properties of chromatin. It is of particular relevance in carcinogenesis, as it represents an e
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