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Effect of VP-16-213 on the intracellular degradation of DNA in HeLa cells

โœ Scribed by Loike, John D.; Horwitz, Susan B.

Book ID
126870399
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
587 KB
Volume
15
Category
Article
ISSN
0006-2960

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โœ Joseph Aisner; Margaret Whitacre; David A. VanEcho; Margaret Wesley; Peter H. Wi ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer ๐ŸŒ English โš– 742 KB

Small cell lung cancer requires aggressive combination chemotherapy. The three active agents, doxorubicin (A) 45 mg/m2 i.v. day 1, cyclophosphamide (C) 1.0 mg/m2 i.v. day 1 and VP16-213 (E) 50 mg/m2/day i.v. days 1-5 were given together. The combination (ACE) was given every 21 days without chest ir