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Effect of vitamin D3 on interleukin-6 synthesis induced by prostaglandins in osteoblasts

โœ Scribed by O. Kozawa; H. Tokuda; T. Kaida; H. Matsuno; T. Uematsu


Book ID
117642663
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
403 KB
Volume
58
Category
Article
ISSN
0952-3278

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Effects of vitamin D3 on signaling by pr
โœ Haruhiko Tokuda; Jun Kotoyori; Atsushi Suzuki; Yutaka Oiso; Osamu Kozawa ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 602 KB

We investigated the effects of vitamin D3 on the signaling pathways by prostaglandin E, (PGE2) in osteoblast-like MC3T3-El cells. The pretreatment with 1,25-dihydroxyvitamin D3 (1 ,25-(OH),D3), an active form of vitamin D3, significantly inhibited cAMP accumulation induced by 10 (LM PGE, in a dose-d