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Effect of verapamil on the growth and vincristine sensitivity of human tumors transplanted under the mouse kidney capsule

✍ Scribed by I. V. Storozhenko; N. S. Sergeeva; V. I. Chissov; O. I. Skotnikova

Book ID: 105578400
Publisher: Springer US
Year: 1996
Tongue: English
Weight: 252 KB
Volume: 121
Category: Article
ISSN: 0007-4888
DOI: 10.1007/bf02447133

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Verapamil, a calcium channel blocker, is used as the racemate. Recently, racemic verapamil has been shown to increase the cytotoxicity of vinca alkaloid and anthracycline derivatives in several resistant tumour cell lines. With respect to its cardiovascular activity S-verapamil is an order of magnit