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Effect of various iron chelating agents on DNA synthesis in human cells

✍ Scribed by Kanasagabai Ganeshaguru; A.Victor Hoffbrand; Robert W. Grady; Anthony Cerami

Book ID
115775148
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
496 KB
Volume
29
Category
Article
ISSN
0006-2952

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✍ George J. Kontoghiorghes; Andrea Piga; A. Victor Hoffbrand πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 613 KB

Cytotoxic and DNA synthesis inhibitory effects of several iron chelators with different physicochemical properties have been tested in four myeloid leukaemic cell lines (U937, K562, ML2 and HL60). The small lipophilic chelators 8-hydroxyquinoline, tropolone an5d omadine at 2 x lo-%, caused substanti