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Effect of valproic acid on zinc metabolism in the rat

โœ Scribed by Daffron, Jan Campbell; Kasarskis, Edward J.


Book ID
122938029
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
304 KB
Volume
23
Category
Article
ISSN
0378-4274

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Valproic acid (WA) is an anticonvulsant agent which produced marked choleresis in the rat. Bile flow rate increased from 50 to 60 pl per min per kg to 120 to 145 p1 per min per kg immediately after i.v. injection of VPA (37.5 to 150 mg per kg; 2 ml per kg) in male Sprague-Dawley rats. The duration o