The effects of extracellular P, and Na' on cellular Pi concentration and transport were studied. Steady-state P, exchange flux was measured by 3zP uptake in the presence and absence of Na'. Model experiments were also conducted to assess t h e possibility that hydrolysis of organic phosphate esters
Effect of Valinomycin on Net Sodium and Potassium Transport in Ehrlich Ascites Tumour Cells
โ Scribed by LEVINSON, CHARLES
- Book ID
- 109659705
- Publisher
- Nature Publishing Group
- Year
- 1967
- Tongue
- English
- Weight
- 209 KB
- Volume
- 216
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/216074a0
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The effect of extracellular Pi and arsenate on Pi-transport in Ehrlich ascites tumor cells has been studied. Pi-transport can be described by Michaelis-Menten kinetics; the maximal flux equal to 44 mmoles (kg cell water)-' hour-' and K m equal to 3.3 X 1 0 -4 M. Arsenate is a competitive inhibitor o
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