Effect of urapidil on the performance of ischemic myocardium in anesthetized dogs
โ Scribed by H. Schad; W. Heimisch; A. Barankay; S. hesse; N. Mendler
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 543 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0300-8428
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The electrophysiological effects of urapidil, a new aradrenoceptor antagonist, were assessed in the reserpinized guinea-pig ventricular myocardium. Urapidil suppressed the maximal rate of rise (Vm~) of steady-state action potentials elicited by the fast responses at high concentrations independently
Magnesium sulfate, reportedly clinically effective against some ventricular arrhythmias, has not been extensively studied for its effects on experimental ischemic and reperfusion arrhythmias. We evaluated the effects of three high extracellular concentrations of magnesium (Mg2+) 1.19, 2.38, and 4.76