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Effect of UDP-glucuronosyltransferase 1A8 polymorphism on raloxifene glucuronidation

✍ Scribed by Kokawa, Yuki; Kishi, Naoki; Jinno, Hideto; Tanaka-Kagawa, Toshiko; Narimatsu, Shizuo; Hanioka, Nobumitsu

Book ID
121189972
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
370 KB
Volume
49
Category
Article
ISSN
0928-0987

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Variation of hepatic glucuronidation: No
Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4
✍ Ursula Ehmer; Arndt Vogel; Jan Karl SchΓΌtte; Britta Krone; Michael P. Manns; Chr πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 138 KB

UDP-glucuronosyltransferases are a family of drug metabolizing enzymes contributing to hepatic drug metabolism and protection against environmental toxins. The aim of this study was to identify polymorphisms at the human UGT1A gene locus and to characterize their function and potential association w