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Effect of tropolone on the binding of [3H]colchicine to brain tubulin

✍ Scribed by Sushil K. Kalra; M. Fragata

Book ID: 115904321
Publisher: Elsevier Science
Year: 1974
Tongue: English
Weight: 305 KB
Volume: 42
Category: Article
ISSN: 0014-5793
DOI: 10.1016/0014-5793(74)80292-9

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## Abstract Colchicine blocks axoplasmic flow and produces neurofibrillary degeneration. Brain slices from mice injected intracerebrally with colchicine incorporated more [^14^C]leucine into protein and had a decreased uptake of [^14^C]leucine into the perchloric acid‐soluble pool than did their co