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Effect of Triple Costimulation Blockade on Islet Allograft Survival in Sensitized Mice

✍ Scribed by R. Diab; T. Iwata; M. Corbascio; A. Tibell; H. Ekberg; J. Holgersson; M. Kumagai-Braesch

Book ID
116936359
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
97 KB
Volume
42
Category
Article
ISSN
0041-1345

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## Abstract This study was performed to observe the long‐term effect of FTY720 on lymphocyte count change and islet allograft survival. Diabetic C57BL/6 mice were given FTY720 (group 1, 0.5 mg/kg/day; group 2, 1.0 mg/kg/day) or its vehicle (group 3, controls) after transplantation. Median graft sur