Effect of tris-(hydroxymethyl)-aminometh
β
Seigo Nagao; Takuji Kitaoka; Kei Fujita; Hideyuki Kuyama; Motoomi Ohkawa
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Article
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1996
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Springer-Verlag
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English
β 624 KB
Systemic and focal cerebral acidosis is considered deleterious to cell metabolism and neuronal recovery. We investigated the immediate effect of tris-(hydroxymethyl)-aminomethane (THAM), an alkalizing agent, on focal cerebral ischemia produced by occlusion of the left middle cerebral artery (MCA) in