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Effect of transforming growth factor-beta1 on expression of the connective tissue growth factor (CCN2/CTGF) gene in normal human gingival fibroblasts and periodontal ligament cells

✍ Scribed by H. Takeuchi; S. Kubota; E. Murakashi; T. Fukada; S. Hashimoto; M. Takigawa; Y. Numabe


Book ID
111262104
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
402 KB
Volume
44
Category
Article
ISSN
0022-3484

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## Abstract Connective tissue growth factor (CTGF/CCN2) is a matricellular protein induced by transforming growth factor (TGF)‐β and intimately involved with tissue repair and overexpressed in various fibrotic conditions. We previously showed that keratinocytes in vitro downregulate TGF‐β‐induced e