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Effect of Trace Levels of Nigericin on Intracellular pH and Acid-Base Transport in Rat Renal Mesangial Cells

✍ Scribed by M.O. Bevensee; E. Bashi; W.F. Boron

Publisher
Springer
Year
1999
Tongue
English
Weight
538 KB
Volume
169
Category
Article
ISSN
0022-2631

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✍ Dennis J. Pillion; Lamar Moree; Hector Rocha; David H. Pashley; Joseph Mendicino πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 599 KB

The effects of diamide were studied in rat kidney cortical tissue. It was found that diamide increased oxidized glutathione levels and inhibited Na+-K+-ATPase activity. Consistent with this finding was the observation that diamide compromised the sodium gradients maintained in renal cortical slices.