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Effect of thymoleptics on fenfluramine-induced depletion of brain serotonin in rats

โœ Scribed by D. Ghezzi; R. Samanin; S. Bernasconi; G. Tognoni; M. Gerna; S. Garattini


Book ID
118321188
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
368 KB
Volume
24
Category
Article
ISSN
0014-2999

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Various effects of chlorpheniramine (CPA), diphenhydramine (DIPH), tripelennamine (TRIP), and pyrilamine (PYRI) on fenfluramine (FEN)-induced depletion of serotonin in the brain of rats were observed to be dependent on body temperature. Levels of 5-HT and 5-HIAA in the frontal cortex, hippocampus, a