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Effect of thromboxane synthetase inhibitors (OKY-046,OKY-1580) on the action of bronchoactive agents in guinea pig tracheal strips and on arachidonate metabolism in guinea pig lung lobes

โœ Scribed by Satoshi Kitamura; Yoko Ishihara; Fumimaro Takaku


Book ID
113301479
Publisher
Elsevier Science
Year
1984
Weight
531 KB
Volume
14
Category
Article
ISSN
0262-1746

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โœ M. Kurosawa; H. Tsukagoshi ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier ๐ŸŒ English โš– 350 KB

SUMMARY: We studied the effect of iv administration of leukotriene (LT) \(\mathrm{C}_{4}\) on bronchial responsiveness to histamine and airway wall thickening in guinea-pigs. The infusion of \(3 \mu \mathrm{g} / \mathrm{kg} \mathrm{LTC}\) for \(1 \mathrm{~h}\) induced an increase of the relative thi