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Effect of a thromboxane A2 synthetase inhibitor (OKY-046 · HCl) on airway hyperresponsiveness in guinea pigs

✍ Scribed by Hidetada Komatsu; Yasuo Takehana; Shinji Kikuchi; Masami Kojima; Shuichiro Hamano; Hiroshi Kusama; Tadao Okegawa; Shigeru Ikeda

Book ID
115883546
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
683 KB
Volume
184
Category
Article
ISSN
0014-2999

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📜 SIMILAR VOLUMES

Inhibitory Effect of a Thromboxane A2 Sy
Inhibitory Effect of a Thromboxane A2 Synthetase Inhibitor OKY-046 on Bronchial Hyperresponsiveness to Histamine, but not on Airway Wall Thickening, Induced by Intravenous Administration of Leukotriene C4 in Guinea-pigs
✍ M. Kurosawa; H. Tsukagoshi 📂 Article 📅 1993 🏛 Elsevier 🌐 English ⚖ 350 KB

SUMMARY: We studied the effect of iv administration of leukotriene (LT) \(\mathrm{C}_{4}\) on bronchial responsiveness to histamine and airway wall thickening in guinea-pigs. The infusion of \(3 \mu \mathrm{g} / \mathrm{kg} \mathrm{LTC}\) for \(1 \mathrm{~h}\) induced an increase of the relative thi