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Effect of OKY-046, a selective thromboxane (TX)A2 synthetase inhibitor, on airway hyperresponsiveness models of guinea pig

โœ Scribed by H. Komatsu; Y. Takehana; S. Hamano; S. Hiraku; S. Ikeda


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
79 KB
Volume
10
Category
Article
ISSN
0192-0561

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Inhibitory Effect of a Thromboxane A2 Sy
โœ M. Kurosawa; H. Tsukagoshi ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier ๐ŸŒ English โš– 350 KB

SUMMARY: We studied the effect of iv administration of leukotriene (LT) \(\mathrm{C}_{4}\) on bronchial responsiveness to histamine and airway wall thickening in guinea-pigs. The infusion of \(3 \mu \mathrm{g} / \mathrm{kg} \mathrm{LTC}\) for \(1 \mathrm{~h}\) induced an increase of the relative thi