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Effect of the structural isomer N-3-fluorenylacetamide on microsomal binding and hydroxylation of the carcinogen N-2-fluorenylacetamide

โœ Scribed by Yeh Mei Chow; Helmut R. Gutmann; Eli Kaplan

Book ID
115775731
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
925 KB
Volume
30
Category
Article
ISSN
0006-2952

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A novel assay of glucuronidation of C- a
A novel assay of glucuronidation of C- and N-hydroxylated metabolites of the carcinogen N-2-fluorenylacetamide
โœ Casimir N. Ryzewski; Danuta Malejka-Giganti ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 593 KB

A method for the assay of glucuronidation of C- and N-hydroxylated metabolites of the carcinogen N-2-fluorenylacetamide is described. The method employs UDP-[U-14C ))glucuronic acid and Baker C18 extraction columns for separation of the glucuronides from their aglycones and from the glucuronic acid.