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Effect of the serine-borate complex on the relative ability of leukotriene C4, D4 and E4 to inhibit lung and brain [3H]leukotriene D4 and [3H]leukotriene C4 binding: Demonstration of the agonists' potency order for leukotriene D4 and leukotriene C4 receptors

✍ Scribed by John B. Cheng; Robert G. Townley

Book ID
117056596
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
254 KB
Volume
119
Category
Article
ISSN
0006-291X

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## Abstract A new method for the synthesis of highly deuterated or tritiated leukotrienes was developed. The higher reactivity of a terminal alkene compared to a 1,2‐disubstituted one permitted the selective deuteration or tritiation of the diyne 14,15,19,19,20,20‐hexadehydro LTC~4~ triester 1. Aft