Moloney leukemia virus-specific cytotoxic T lymphocytes (CTL), generated by secondary in vitro stimulation of spleen cells with syngeneic virusinfected cells, frequently lysed not only syngeneic virus-infected cells, but also noninfected allogeneic target cells. This phenomenon was studied with B6(H
β¦ LIBER β¦
Effect of the Ly2 molecule on the function of alloantigen-specific effector cytotoxic T-lymphocytes in relationship to the variation of T-cell receptor affinity
β Scribed by I. A. Popov; B. D. Brondz; N. G. Anosova; Yu. S. Krivoshein; V. V. Kronin
- Publisher
- Springer US
- Year
- 1993
- Tongue
- English
- Weight
- 277 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0007-4888
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## Abstract The present study investigates the role of nonβHβ2 genes in controlling generation of the Hβ2βrestricted, T cellβmediated cytotoxic response against trinitrophenyl (TNP)βmodified syngeneic cells (TNPβself). Spleen cells from C3H/He (Hβ2^k^) or B10.BR (Hβ2^k^) normal mice or from mice pr