Effect of the glutamine synthetase inhibitor, methionine sulfoximine, on the growth and differentiation of Dictyostelium discoideum
โ Scribed by Andrew J Dunbar; John F Wheldrake
- Book ID
- 109321804
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 677 KB
- Volume
- 151
- Category
- Article
- ISSN
- 0378-1097
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Indirect immunofluorescence with antibodies to microtubular proteins has been used to investigate the microtubule system of __Dictyostelium discoideum__ vegetative amoebae and the action of several compounds that interfere with that system. All the inhibitors tested show an antimicrotub
a d w m , TV'zsconsin INTRODUC'I'TON
Beta amyloid peptides (AP), etiologically associated with Alzheimer's disease (AD), have been shown to inhibit both glutamine synthetase (GS) and creatine phosphokinase (CPK) in vitro. These two enzymes are affected in AD and are sensitive to oxidative stress. Residue 35 of the AP25-35, the most pot