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Effect of the anti-factor Xa and anti-factor IIa activities of low-molecular-weight heparins upon the phases of thrombin generation

✍ Scribed by G. T. GEROTZIAFAS; A. D. PETROPOULOU; E. VERDY; M. M. SAMAMA; I. ELALAMY

Book ID
109152054
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
704 KB
Volume
5
Category
Article
ISSN
1538-7933

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The synthesis of tri-N-acetylated heparin pentasaccharide 2 is described. It was assembled from five suitably blocked monosaccharide units (S7). Glucuronic-acid building block 4 was prepared from glucose by direct Jones oxidation of the 6-0-trityl derivative 18. The resulting acid 16 was esterified