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Effect of the alkylating agent triethyleneiminobenzoquinone on the synthesis of DNA and on the incorporation of [3H]lysine into nuclear proteins of Ehrlich ascites tumor cells

โœ Scribed by H. Wolf; G. Raydt; B. Puschendorf; H. Grunicke


Book ID
115903577
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
297 KB
Volume
35
Category
Article
ISSN
0014-5793

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โœ Iris H. Hall; Y. F. Liou; K. H. Lee ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 551 KB

o Molephantinin, a germacranolide, has previously been shown to possess antineoplastic activity in rodents. The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in uiuo and in uitro. DNA synthesis was inhibited a t the following sites