𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of the 3- and 4-Methyl Groups on the Opioid Receptor Properties of N-Substituted trans -3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines

✍ Scribed by Kormos, Chad M.; Cueva, Juan Pablo; Gichinga, Moses G.; Runyon, Scott P.; Thomas, James B.; Brieaddy, Lawrence E.; Mascarella, S. Wayne; Gilmour, Brian P.; Navarro, Hernán A.; Carroll, F. Ivy


Book ID
121729423
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
334 KB
Volume
57
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of N- Substituted 4-(4-Hydroxy
✍ Guzikowski, Anthony P.; Tamiz, Amir P.; Acosta-Burruel, Manuel; Hong-Bae, Soo; C 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 337 KB

Antagonists at the 1A/2B subtype of the NMDA receptor (NR1A/2B) are typically small molecules that consist of a 4-benzyl-or a 4-phenylpiperidine with an ω-phenylalkyl substituent on the heterocyclic nitrogen. Many of these antagonists, for example ifenprodil (1), incorporate a 4-hydroxy substituent