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Effect of TGF-β1 on the expression of IL-12, IL-15, IL-18, IL-4 and IL-10 in heart transplantation rejection in rats

✍ Scribed by Jinping Zhao; Ping Li; Sihai Gao; Xianguo Wang; Xiaojian Gao

Book ID
107405670
Publisher
Springer-Verlag
Year
2007
Tongue
Chinese
Weight
177 KB
Volume
27
Category
Article
ISSN
0510-9752

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## Abstract In Th1 and Th2 memory lymphocytes, the genes for the cytokines interleukin (IL)‐4 and interferon‐γ (IFN‐γ) are imprinted for expression upon restimulation. This cytokine memory is based on expression of the transcription factors T‐bet for IFN‐γ, and GATA‐3 for IL‐4, and epigenetic modif