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A study on the expression of interleukin(IL)-10 and IL-12 P35, P40 mRNA in the psoriatic lesions

✍ Scribed by Jiqun, Cheng ;Yating, Tu ;Jiawen, Li ;Changzheng, Huang ;Zhixiang, Liu ;Daofan, Liu

Publisher: Springer-Verlag
Year: 2001
Tongue: English
Weight: 443 KB
Volume: 21
Category: Article
ISSN: 0257-716X
DOI: 10.1007/bf02888047

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## Abstract In Th1 and Th2 memory lymphocytes, the genes for the cytokines interleukin (IL)‐4 and interferon‐γ (IFN‐γ) are imprinted for expression upon restimulation. This cytokine memory is based on expression of the transcription factors T‐bet for IFN‐γ, and GATA‐3 for IL‐4, and epigenetic modif