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Effect of TGF-β on Dehydroepiandrosterone Sulfotransferase in Cultured Human Fetal Adrenal Cells

✍ Scribed by C. R. PARKER Jr; A. K. STANKOVIC; C. N. FALANY; W. E. GRIZZLE

Book ID
119871512
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
282 KB
Volume
774
Category
Article
ISSN
0890-6564

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We examined the effects of transforming-growth factor-B (TGF-B) on growth ([3H]-thymidine uptake) and function (dehydroepiandrosterone sulfate [DHAS] and cortisol production) of human fetal zone adrenal cells. Results indicate that TGF-B significantly inhibits, in a dose-related manner, both basal a