Reduction of the 2-methyl-2-p-tolylmalonic monoester (+)-2 with the borane-dimethylsulfide complex took place unexpectedly on the ester function,providing the 8-hydroxy-acid (-)-3. This chemoselective reaction proceeded likely through formation of a six-membered ring monoacyloxyborane intermediate 6
β¦ LIBER β¦
Effect of temperature on borane reduction of representative malonic acids
β Scribed by Choi, Yong M.; Emblidge, Robert W.; Kucharczyk, Norbert; Sofia, R. Duane
- Book ID
- 121423602
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 595 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Reverse chemoselective borane reduction
β
Antoine Fadel; Jean-Louis Canet; Jacques Salaun
π
Article
π
1989
π
Elsevier Science
π
French
β 251 KB
Substituent effects on the reductions of
β
Brent K. Blackburn; John F. Frysinger; David E. Minter
π
Article
π
1984
π
Elsevier Science
π
French
β 222 KB
Effect of the Temperature on the Stoichi
β
Bonnat, M.; Hercouet, A.; Corre, M. Le
π
Article
π
1991
π
Taylor and Francis Group
π
English
β 143 KB
Effect of reduction temperature on inter
β
Kirk A. Rogers; Kevin P. Trumble
π
Article
π
1998
π
Elsevier Science
π
English
β 442 KB
Effect of borane source on the enantiose
β
Xiao Wang; Juanjuan Du; Han Liu; Da-Ming Du; Jiaxi Xu
π
Article
π
2007
π
John Wiley and Sons
π
English
β 174 KB
## Abstract The effect of borane source on enantioselectivity in the enantiopure oxazaborolidineβcatalyzed asymmetric borane reduction of ketones has been investigated by using (__S__)β3,1,2βoxazaborobicyclo[3.3.0]octane and (__S__)β7,3,1,2βthiaxazaborobicyclo[3.3.0]octane as catalysts. The results
Effect of Temperature on the Enantiosele
β
Jiaxi Xu; Tiezheng Wei; Qihan Zhang
π
Article
π
2004
π
John Wiley and Sons
β 170 KB
π 1 views