Effect of taurine on alcoholic liver disease in rats
β Scribed by Gaofeng Wu; Jiancheng Yang; Changmian Sun; Xinhong Luan; Jiao Shi; Jianmin Hu
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 625 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0939-4451
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## Methods: The effect of zinc supplementation on antipyrine clearance was evaluated in 14 outpatients with stable alcoholic liver disease, of whom nine had biopsy proven alcoholic cirrhosis. Results: There was no change in antipyrine clearance after 14 days of zinc supplementation (median 12.5 vs
Long-term ethanol feeding has been shown to selectively reduce hepatic mitochondrial glutathione content by impairing mitochondrial uptake of this thiol. In this study, we assessed the role of this defect in evolution of alcoholic liver disease by examining the mitochondrial glutathione pool and lip