Effect of T cell subset dose on outcome of T cell-depleted bone marrow transplantation
โ Scribed by Kawanishi, Y; Passweg, J; Drobyski, W R; Rowlings, P; Cook-Craig, A; Casper, J; Pietryga, D; Garbrecht, F; Camitta, B; Horowitz, M
- Book ID
- 110010139
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 406 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0007-1188
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๐ SIMILAR VOLUMES
Major ABO-mismatched bone marrow transplantation (BMT) may be accompanied by red-cell haemolysis, but pure red-cell aplasia following BMT is a rare complication. Two cases of transient pure red-cell aplasia following T-lymphocyte-depleted BMT for a period of greater than 20 weeks are described, both
Depletion of T-lymphocytes from allogeneic marrow prior to transplantation decreases the risk of serious graft versus host disease (GvHD), but also increases the risk of relapse. We have used a partial T-cell depletion technique, in the hope of controlling GvHD without compromising relapse risk. All